Man found missing 90% of his brain defies scientific understanding - most of his skull is filled with water:
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(07)61127-1/fulltext
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I ran a lot of MRIs for my PhD. I saw somewhere around 100-200 different brains. About 10% of them had abnormalities. Of all the technicians, scientists, and (non-clinical) doctors I spoke with, we all agreed this was a very high rate of discovery. All my friends graduated without seeing anything weird. My advisor liked to joke that I was cursed. Eventually I stopped inviting my friends to do my experiments because I didn’t want to deal with the risk of them having an abnormality - thanks to some combination of HIPAA and medical liability laws, I wasn’t allowed to say anything about it, even if asked point blank. I didn’t like that very much.
I made one exception, as a friend of mine came in for a study and I saw a golf ball sized cyst in his sinus. He had it surgically removed and he told me he stopped snoring the next day. It felt good to make a difference for him.
But, I saw one brain similar to the one documented here. It belongs to one of my close friends. It was harrowing. Entire left hemisphere was malformed, the ventricles were way too big and the cortex was way too thin. But the right side of his brain was underdeveloped, maybe the size of a tennis ball.
The weirdest part, he is 100% normal. In fact, he competed at a high level of college athletics. Normal Cognition, normal motor function, great sense of humor, and a very caring person. Now he has a great job, wife and kid, and we hang out often. But I can’t bring myself to say anything, and every time I see his son I wonder about his brain.
I’m a Neuroradiologist and occasionally people ask me “Have you ever scanned your own brain?” when they find out my profession.
Abso-fucking-lutely not. I’ve seen how many people have random abnormalities that are unknown until discovered incidentally when having an unrelated problem evaluated. Finding something abnormal in my brain would no doubt keep me up at night even if it was something medically considered unimportant. No way I’m going to scan myself just for fun.
I can just imagine you at their garden party, sweating, while your friend brags how their son is doing so well at school but seems to just not understand some really mundane topic.
Eh, I don’t think autism is related to the appearance of brain.
Love your username, especially with that context 😁
I’m curious, what exactly are you worried about with your friend? Are the abnormalities you saw linked to a treatable disease?
Nope, not related to any disease I’ve ever seen. The best guess i have is fetal alcohol syndrome but it isn’t a perfect match. It’s just weird knowing he has a very odd shaped brain. And there’s a lot of unknowns surrounding it.
What if he sees another doctor and they mention it to him? Would he be upset I didn’t say anything? What if it is linked to some disease and I didn’t tell him, and he gets sick?
What if it’s hereditary and his kid has it, does it explain the motor delays? The premature birth? The problems they have with him sleeping?
Just a lot of unknowns.
You can tell him he should get a second mri that isn’t bound by your rules.
$$$
Sure but then it’s their call and resolves the if they find out issue.
Could you tell him just “you should have another MRI at a clinic”?
That rule does not seem very ethical to me, in any case.
In the US getting an MRI for “no reason” can be very expensive. Probably wouldn’t have been covered by insurance.
Could you release the already captured images for him to take to a doctor for medical advice?
Personally, if I had something like that, that wasn’t causing me problems and wasn’t linked to future problems, I wouldn’t want to know. Especially because of how unknown it is. It sounds like there’s no way that information could be of use to anyone other than a researcher, so it actually seems right that you can’t share it.
On the other hand, I’m glad your other friend got their sinus checked out.
Imagine what would happen if we substituted the water for more brain.
Well it’s not quite water, it’s cerebrospinal fluid and it plays a lot of important roles in waste clearance, immune protection, protection from concussion, and more.
It’s also a refreshing beverage
My advisor liked to joke that I was cursed.
It didn’t have quite the same level of personal impact, but I used to associate with a geologist who said something similar about me and geodes.
Kept finding geodes filled with fresh human blood huh?
“Fresh” might be a stretch.
I think I read that brains like these are basically normal in terms of structure and number of neurons, just compressed by the extra fluid pressure.
He’s not 100% normal, you just haven’t experienced the things he cannot process properly or at all, which is likely a lot of higher reasoning… They just don’t affect his day to day, which gives us clues that day to day functioning is very low level and likely mostly autonomous.
Eh, college is hard and so was his sport. Sure, it’s not an exhaustive battery of testing but I’m confident to say he’s a normal dude.
Average middle manager
I have SO many questions
Holy shit. That’s fucking wild. I know the brain is adaptable, particularly to things that occur during childhood, but… damn.
When I got an MRI I learned I have some empty spaces in my brain that normally close during infancy. I was there because my family has a genetic marker for cavernous venous malformations primarily in the brain. Luckily it doesn’t affect our intelligence, we just “die of headaches”.
F
Also, you’d think the title was edited for meme-ing purposes…but no. This is just dead ass what they printed in The Lancet 😂
Every time this is mentioned I get the biggest chuckle out of him being a French civil servant.
Explains why it went unnoticed.
If we could just let go of the Yakubian myth that more brains = smarter, this wouldn’t be so surprising.
That man very certainly uses 100% of his brain.
Isn’t it expected for a brainless human to defie science?
We’ve actually seen a handful of them in the community. MIT has an “Interesting Brain Project” https://news.mit.edu/2023/studies-of-unusual-brains-reveal-insights-brain-organization-function-0221.
If you’re born that way, odds are you’ll be more or less normal. It’s amazing to see how resilient the human brain is.
In fact, one woman in China was born without a cerebellum. She wasn’t exactly normal per se, but she was alive and more or less healthy. Even though the cerebellum is smaller by volume it has about the same number of neurons as the cerebrum. So she just had half a brain. https://www.newscientist.com/article/mg22329861-900-woman-of-24-found-to-have-no-cerebellum-in-her-brain/
a brainless human to [defy] science
I think you spelled ‘politics’ wrong.
Brainless people LOVE politics. They consider themselves the biggest specialists in politics.
Yaaay, new nightmare unlocked!
Weird, you can just make out letters in one angle, i see a M and G… Was the subject wearing a hat during the scan?
