Although it may not be ideal for a large document, I have used the Coblis for individual figures that I’m worried about. I usually find small tweaks to the colors can make them much more readily differentiable in the simulator.

You don’t need to do this. If properly pruned, crape myrtles will form a canopy over the sidewalk that doesn’t interfere with pedestrians and actually provides shade; if topped like the picture, they will form an unruly mass of growth right at head height.

Atomic Frontier on YouTube trained a machine learning model on his prior emails, assignments, etc., and had it determine his personal worst keyboard layout. He posted the code on GitHub for others to do the same.